You can get common denominator in the denominator of the original fraction so it would look like:
[tex] \frac{4}{ \frac{1}{4}- \frac{10}{4} } = - \frac{1}{ \frac{9}{4} } [/tex]
You can reciprocalize and then multiply:
[tex]4* -\frac{4}{9} = -\frac{16}{9} [/tex]
So, your answer is C.
