Explanation:
A rare genetic diseasearises from mutations in subunits of TAP (TAP 1 or TAP 2). The individuals with this disease are susceptable to recurrent infections.
The efforts could be expected from this mutation- MHC class II molecules will not be loaded with peptides, so CD8+ T cells cannot be activated. MHC class I molecules will not be loaded with peptides, so CD4+T cells cannot be activated MHC class I molecules will not be loaded with peptides, so CD8+T cells without be activated.
